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All data that support the findings of this study are available on reasonable request to the corresponding authors. The contributing authors declare that all relevant data are included in the paper and its supplementary information files. Abstract Some genetic melanocortin-1 receptor MC1R variants responsible for human red hair color RHC-variants are consequently associated Beautiful mature looking sex personals Charleston South Carolina increased melanoma risk. Although MC1R aling is critically dependent on its palmitoylation primarily mediated by the ZDHHC13 protein-acyl transferase, whether increasing MC1R palmitoylation represents a viable therapeutic target to limit melanomagenesis in redhe is unknown.

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